Chronic pain related with tissue injury is termed as neuropathic pain. Neurosurgery plays a huge impact on such neuropathic pain. The impact of nerve fibre injury includes a change in nerve function both at the site of injury and areas around the injury. Nerve pressure or nerve damage after surgery or trauma along with viral infections, cancer, and even vascular malformations, alcoholism, neurological conditions such as multiple sclerosis and metabolic conditions such as diabetes are the common cause of neuropathic pain. Peripheral neuropathic pain, central neuropathic pain, or mixed (peripheral and central) neuropathic pain is the three-basic mechanism of neuropathic pain. Statistics says that 7- 8% of the European population is affected, out of which 5% of patients are severely traumatized. Anti-epileptics, Antidepressants, Opioids, Transcutaneous electrical nerve stimulation (TENS) and percutaneous electrical nerve stimulation (PENS) are the few treatment processes for neuropathic pain.